Originally a mutant paratrooper from the future, Bishop has gone through a bunch of character shifts, due largely to Marvel’s inability to figure out his place in the Marvel Universe; he’s been an X-Man, he’s been an alternate reality savior, he’s been a warrior in a post-apocalyptic future.
Bishop works with NYPD patrolman Ismael Ortega, an ordinary human married to a mutant (Armena Ortega). A major subplot is Ismael's relationship with his family, with the stresses of his job adversely affecting his home life.
Volume 1, or Mr. X, begins as violence erupts between rival crime lords “Shaky” Kaufman and “Filthy Frankie” Zapruder over a mutant, Toad Boy, and the addictive narcotic he produces (known as 'Toad Juice'). (his mother is obsessed and addicted to this toad juice and some very disturbing scenes where she licks his neck to get it.)
When Kaufman learns of the sales of 'Toad Juice' in District X, he raids Zapruder’s facilities and kidnaps the Toad Boy for himself. But, it’s unknown that Toad Juice can be fatal to humans and a theft of the drug leads to the death of over a dozen human teenagers at a party.
After the death of a human patron at the nightclub Daniel’s Inferno caused by exposure to Toad Juice, the police begin a desperate investigation before other unsuspecting addicts face the same fate. This prompts a turf war between Zapruder and Kaufman. Both men are eventually arrested.
When Absolom Mercator, “Mr. M“, finally decides to use his powers to try and help others, his efforts backfire and he suffers an intense identity crisis. Believing that he must use his powers to destroy Mutant Town, Mr. M warns his friend, Hanna Levy so that she can escape safely. The police intervene and use Lara the Illusionist to show Mr. M the devastation he could unleash. This snaps the mutant back to his senses and he willingly returns to his peaceful life of quiet isolation after a short period in jail.
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